Mood Disorder Questionnaire (MDQ)
A 13-item self-report screen for bipolar spectrum disorder, with two follow-up questions. For the symptom items, answer about whether there has ever been a period when you were not your usual self and the statement was true. A positive screen requires 7 or more symptoms endorsed, co-occurrence during the same period, and at least moderate functional impairment. Administer under clinician oversight.
This is a clinical instrument. It is not publicly self-administered — a clinician assigns it through a secure patient link.
At a glance
What it measures
The Mood Disorder Questionnaire (Hirschfeld et al., 2000) screens for bipolar spectrum disorder with 13 yes/no symptom items — answered about any lifetime period of not being one's usual self — plus two follow-up questions on co-occurrence and functional impact.
A positive screen requires all three published criteria at once: seven or more symptom items endorsed, the symptoms co-occurring in the same period, and at least moderate impairment. This three-criterion rule is applied exactly as published; meeting it indicates that bipolar-spectrum evaluation is warranted, not that a diagnosis is established.
Psychometric properties
The notes below are reproduced from the platform's psychometrics register for this instrument — the same source-cited reliability, validity, and norms text that accompanies its downloadable report.
Adequate internal consistency for the 13 symptom items (alpha around 0.90) (Hirschfeld et al., 2000).
In the original validation the full positive-screen algorithm achieved sensitivity 0.73 and specificity 0.90 in a psychiatric sample (Hirschfeld et al., 2000); sensitivity is lower in general and community samples.
Developed in US outpatient psychiatric clinics; the instrument performs best in clinical populations.
Subscales
Manic/hypomanic symptoms 13 items
Co-occurrence 1 items
Functional impairment 1 items
Example item
“you felt so good or so hyper that other people thought you were not your normal self, or you were so hyper that you got into trouble?”
Illustrative only. During administration items are presented one screen-set at a time; response-key direction is never shown to respondents.
Scoring & interpretation
Scored by the instrument's published three-criterion screening algorithm (symptom count, co-occurrence, and impairment).
Source & citation
Hirschfeld, R. M. A., Williams, J. B. W., Spitzer, R. L., et al. (2000). Development and validation of a screening instrument for bipolar spectrum disorder: the Mood Disorder Questionnaire. American Journal of Psychiatry, 157(11), 1873–1875.
Scoring. A positive screen requires 7 or more symptom items endorsed, co-occurrence during the same period, and at least moderate functional impairment (Hirschfeld et al., 2000).
Mood Disorder Questionnaire (MDQ) © 2000 by Robert M. A. Hirschfeld, MD. Reproduced for clinical and research use with attribution.
References
- Hirschfeld, R. M. A., Williams, J. B. W., Spitzer, R. L., et al. (2000). Development and validation of a screening instrument for bipolar spectrum disorder: the Mood Disorder Questionnaire. American Journal of Psychiatry, 157(11), 1873-1875.
- Hirschfeld, R. M. A., Holzer, C., Calabrese, J. R., et al. (2003). Validity of the Mood Disorder Questionnaire: a general population study. American Journal of Psychiatry, 160(1), 178-180.